Anti-DM1/DM4 monoclonal antibody for ADC has Maytansinoid as the highly toxic payload for antibody drug conjugates. This effectively transports DM1/DM4 to cancer cells, inhibits microtubule formation, halts cell cycle and triggers apoptosis only in cancerous cells but the normal cells are less affected for targeted anti-cancer therapy.
Check the application of
Maytansinoid (DM1/DM4) in ADCs
注文情報
| Catalog No. |
Product Name |
Size |
Price(In USD) |
| GTU-Bios-Maytansinoids-Ab-1 |
Anti-DM1/DM4 (Maytansinoid) human monoclonal antibody (mAb) |
1mg |
1690 |
| GTU-Bios-Maytansinoids-Ab-2 |
Anti-DM1/DM4 (Maytansinoid) mouse monoclonal antibody (mAb) |
1mg |
1690 |
| GTU-Bios-Maytansinoids-Ab-3 |
Anti-DM1/DM4 (Maytansinoid) mouse monoclonal antibody (mAb) |
1mg |
1690 |
Size： 1mg | 10mg | 100mg
説明
Anti-DM1/DM4 (Maytansinoid)
human
monoclonal antibody (mAb)
| Cat No. |
GTU-Bios-Maytansinoids-Ab-1 |
| Product Name |
Anti-DM1/DM4 (Maytansinoid) human monoclonal
antibody (mAb) |
| Target |
Maytansinoid (DM1/DM4) |
| Expression platform |
mammalian cell |
| Isotypes |
Human IgG1 |
| Bioactivity validation |
Maytansinoid (DM1/DM4) binding, Competitive
immunoassay validation (Competitive ELISA) in Maytansinoid (DM1/DM4) level test. |
| Tag |
hFc |
| Products description |
Anti-Maytansinoid (DM1/DM4) monoclonal
antibody is
expressed from mammalian cell. |
| Species |
Human |
| Purity |
Purity: ≥95% (SDS-PAGE) |
| Application |
Competitive immunoassay validation
(Competitive
ELISA) and other Immunoassay, PK & PD assay for DM1/DM4 payload of Antibody-drug
Conjugate (ADC). |
| Formulation |
Lyophilized from sterile PBS, PH 7.4 |
| Storage |
Store at -20℃ to -80℃ under sterile
conditions.
Avoid repeated freeze-thaw cycles. |
Anti-DM1/DM4 (Maytansinoid)
mouse
monoclonal antibody (mAb)
| Cat No. |
GTU-Bios-Maytansinoids-Ab-2,
GTU-Bios-Maytansinoids-Ab-3 |
| Product Name |
Anti-DM1/DM4 (Maytansinoid) mouse monoclonal
antibody (mAb) |
| Target |
Maytansinoid (DM1/DM4) |
| Expression platform |
mammalian cell |
| Isotypes |
Mouse IgG |
| Bioactivity validation |
Maytansinoid (DM1/DM4) binding, Competitive
immunoassay validation (Competitive ELISA) in Maytansinoid (DM1/DM4) level test. |
| Tag |
mFc |
| Products description |
Anti-Maytansinoid (DM1/DM4)) mouse monoclonal
antibody (mAb) is expressed from mammalian cell. |
| Species |
Mouse |
| Purity |
Purity: ≥95% (SDS-PAGE) |
| Application |
Competitive immunoassay validation
(Competitive
ELISA) and other Immunoassay, PK & PD assay for DM1/DM4 payload of Antibody-drug
Conjugate (ADC). |
| Formulation |
Lyophilized from sterile PBS, PH 7.4 |
| Storage |
Store at -20℃ to -80℃ under sterile
conditions.
Avoid repeated freeze-thaw cycles. |
参考文献
Validation Data
Click to get more Data
/ Case study
about the product.
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